Skeletal muscle mitochondrial remodeling in exercise and diseases
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چکیده
منابع مشابه
Ursolic acid induces myoglobin expression and skeletal muscle remodeling in mice
Introduction: Ursolic Acid (UA) is a lipophilic triterpenoid compound, found in large amounts in apple peel. Anabolic effects of UA on the skeletal muscle and the role of this tissue as a key regulator of systematic aging aroused this question in mind whether UA might amend skeletal muscle performances such as myoglobin expression and also whether it switches skeletal muscle fibers from glyc...
متن کاملPhysical exercise and mitochondrial function in human skeletal muscle.
Muscle adaptation to endurance training involves qualitative changes in intrinsic properties of mitochondria. After training, the ADP sensitivity of miitochondrion is decreased whereas the effect of creatine on respiration is increased. This results in an improved control of aerobic energy production. Acute exercise does not adversely affect mitochondrial function.
متن کاملAcute exercise remodels mitochondrial membrane interactions in mouse skeletal muscle
A unique property of mitochondria in mammalian cells is their ability to physically interact and undergo dynamic events of fusion/fission that remodel their morphology and possibly their function. In cultured cells, metabolic perturbations similar to those incurred during exercise influence mitochondrial fusion and fission processes, but it is unknown whether exercise acutely alters mitochondri...
متن کاملNAD + / NADH and skeletal muscle mitochondrial adaptations to exercise 4
1 2 3 NAD/NADH and skeletal muscle mitochondrial adaptations to exercise 4 Amanda T. White and Simon Schenk*. 5 6 Biomedical Sciences Graduate Program and Department of Orthopaedic Surgery, University of 7 California, San Diego. La Jolla, CA 92093. 8 9 * Corresponding Author: Simon Schenk, Department of Orthopaedic Surgery, University of California, 10 San Diego. 9500 Gilman Drive MC0863, La Jo...
متن کاملREVIEWS Intracellular Signal for Skeletal Muscle Adaptation NAD /NADH and skeletal muscle mitochondrial adaptations to exercise
White AT, Schenk S. NAD /NADH and skeletal muscle mitochondrial adaptations to exercise. Am J Physiol Endocrinol Metab 303: E308–E321, 2012. First published March 27, 2012; doi:10.1152/ajpendo.00054.2012.—The pyridine nucleotides, NAD and NADH, are coenzymes that provide oxidoreductive power for the generation of ATP by mitochondria. In skeletal muscle, exercise perturbs the levels of NAD , NAD...
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ژورنال
عنوان ژورنال: Cell Research
سال: 2018
ISSN: 1001-0602,1748-7838
DOI: 10.1038/s41422-018-0078-7